Early evidence shows that ellagic acid acts as a scavenger to "bind" or chemically engage cancer-causing chemicals, making them inactive. In addition, this fused bi-nuclear coumarin derivative prevents the binding of carcinogens to DNA and reduces the incidence of cancer in cultured human cells exposed to carcinogens.

Ellagic acid is widely found in plants such as raspberries, strawberries, blackberries, cranberries, walnuts, and pecans, but the greatest amounts have been observed in raspberries. While the leaves of these plants contain the highest concentrations of ellagic acid, the compound is also found in their fruits and nuts.

Although ellagic acid is the bioactive agent that offers protection, the phytochemical is generally ingested in the form of another biochemical called ellagitannin. Plants produce ellagic acid and glucose that combine to form ellagitannins, which are water-soluble compounds that are easier for animals to absorb in their diets. Consequently, small amounts of ellagitannins derived from natural sources may be more effective in the human diet than large doses of purified ellagic acid.